Community differentiation of the cutaneous microbiota in psoriasis

Microbiome

Table 3 Non-Euclidean multivariate analysis of variance

Factor	df	Sum of squares	Pseudo-F-statistic	P value^a
Body site^b	3	1.363	1.624	0.00015
Cutaneotype	1	0.626	2.236	0.00015
SampleMonthYear	24	10.141	1.510	0.00015
Status	2	0.854	1.526	0.0003
Skin micro-environment	1	0.321	1.141	0.11000
Gender	1	0.363	1.296	0.2940
Ethnicity	3	0.972	1.158	0.3179
Age	1	0.305	1.091	1.0
History	1	0.302	1.080	1.0
Status × body site	6	1.529	0.910	1.0
Status × age	2	0.482	0.862	1.0
Status × sample month year	28	7.265	0.927	1.0
Status × gender	2	0.468	0.837	1.0
Status × ethnicity	6	1.733	1.032	1.0
Status × history	2	0.490	0.876	1.0
Status × cutaneotype	2	0.549	0.981	1.0
Residuals	66	18.471
Total	150	45.913

^aP values are based on 100,000 permutations and are adjusted for multiple testing using the Bonferroni method. Significant values are in bold.
^bBody sites are grouped into head, body, upper extremities, lower extremities.

ISSN: 2049-2618