Differential features in common between ALDEx2, DESeq and baySeq. Genes are colored in light yellow if ALDEx and at least one of the other two tools identified them as significantly different with an fdr <0.05, black if they were identified by both baySeq and DESeq, magenta if only by baySeq, cyan if only by DESeq, and orange if only by ALDEx2. Small gray dots are non-differential genes. The Venn diagram illustrates the number of differentially abundant genes identified by each method. MA, mean difference between conditions vs average expression; MW, mean difference between conditions vs maximum within-condition variance.