Characterization and comparison of bacterial communities in benign vocal fold lesions

Microbiome

Table 3 Mean sequence richness, evenness, and diversity in lesion and HMP samples

	Cysts	Nodules	Polyps	Reinke’s edema	Saliva	Throat
Chao	96.9 ± 23.4^b	121.7 ± 43.5	98.1 ± 15.6^c	90.2 ± 11.6^a	190.1 ± 12.2^abc	140.6 ± 11.5
1/Simpson	7.4 ± 2.9	6.0 ± 2.8	4.0 ± 1.3^e	4.1 ± 1.5^d	17.7 ± 1.6^*	11.0 ± 1.4^de
Shannon	1.9 ± 0.5	1.8 ± 0.6	1.3 ± 0.3^g	1.3 ± 0.3^f	3.4 ± 0.1^**	2.8 ± 0.1^fg
Good’s coverage	0.991 ± 0.002	0.997 ± 0.001	0.994 ± 0.001	0.993 ± 0.001	0.988 ± 0.001	0.992 ± 0.001

Mean Good’s coverage, Chao, inverse Simpson, and Shannon are reported for each of the four lesion types, and saliva and throat samples from the HMP, along with standard error.
^*Saliva was significantly different from all other groups for inverse Simpson (p < 0.0001).
^**Saliva was significantly different from all lesion samples for Shannon, but not throat (p < 0.0001).
^a–gPairwise comparisons that were significantly different (p < 0.0001).

ISSN: 2049-2618