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Fig. 3 | Microbiome

Fig. 3

From: Gut resistome development in healthy twin pairs in the first year of life

Fig. 3

β-lactamase phylogenetic tree. Predicted β-lactamase protein sequences were collapsed into 97 % ID clusters. All β-lactamase protein sequences with at least 90 % coverage of the nearest hit in the NCBI nr database were included in the tree. Multiple alignment was done with Muscle and the tree was made using FastTree. Nodes with an S-H value >0.7 are marked with a square. All classes of β-lactamases are present. Class A β-lactamases separated into two groups: one with high identity to TEM extended-spectrum β-lactamases and one without. β-lactamases co-localized with mobile genetic elements are marked with a gray dot. Novel β-lactamases with less than 70 % identity to any known β-lactamase are marked with a star. β-lactamases found in cefepime selections are marked with a triangle

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