Fig. 4
From: Colitis susceptibility in p47phox−/− mice is mediated by the microbiome
p47phox−/− mice have a distinct intestinal microbiome signature before and after DSS colitis. Bacterial taxonomic classifications show colonization with unique taxa and altered representation of diverse taxa in p47phox−/− compared to B6Tac mice. a Relative abundances of 7 major phyla taxonomies in p47phox−/− and B6Tac mice, as well as p values from P tests are reported for the group comparisons listed for DSS days 0 and 9. b PCoA and p values of the weighted UniFrac comparing p47phox−/− to B6Tac mice on DSS days 0 and 9 are shown. c Heat map depicting average relative abundance by LEfSe of bacterial genera in fecal samples from p47phox−/− and B6Tac mice on DSS day 0 and day 9. Top quartile of OTUs where comparisons between each experimental group were significant (p < 0.05) is shown. Alpha diversity was measured in p47phox−/− and B6Tac mice before and after DSS colitis by inverse Simpson and Shannon diversity (d). Gen. classified as distinct but unnamed genus in Greengenes reference database, sp. designates a distinct species in Greengenes reference database