Fig. 2

Genera strikingly different across groups. a Relative abundance of the top 44 most different genera across groups at the criteria of P value <0.1 by Wilcoxon rank sum test. C, control; P, pHTN; H, HTN. The abundance profiles are transformed into Z scores by subtracting the average abundance and dividing the standard deviation of all samples. Z score is negative (shown in blue) when the row abundance is lower than the mean. Genera at P value <0.01 are marked with dark green star, P value <0.05 with light green star, and P value ≥0.05 with gray circle. b The box plot shows the relative abundance of four genera enriched in pHTN and HTN patients, and 11 genera abundant in control. Genera are colored according to the phylum. Boxes represent the inter quartile ranges, lines inside the boxes denote medians, and circles are outliers