Fig. 5

Central Kdo and lipid A biosynthesis is invariable, but many genes involved in covalent modifications to LPS are variable. a Pathway schematic showing a selection of measured gene families involved in lipopolysaccharide metabolism. Gene families are color-coded by whether they were variable (red) or invariable (blue), with strength of color corresponding to the FDR cutoff (color intensity). Central Kdo and lipid A metabolism is highlighted in light gray. Abbreviated metabolites are (GlcNAc N-acetylglucosamine), (Kdo ketodeoxyoctonate), (R5P ribose-5-phosphate), (S7P sedoheptulose-7-phosphate), (GMH glyceromannoheptose), (aminoarabinose 4-amino-4-deoxy-L-arabinose). b Heatmaps showing scaled residual log-RPKG for gene families (rows) involved in lipopolysaccharide metabolism, as in Fig. 4