Fig. 4

Inter-individual variability of gut microbiota features. Data were filtered based on the mean relative abundance of the features in the sample cohort (threshold >0.01%). a Cladogram illustrating taxa with CV >150% (variable, darker color) or <60% (conserved, lighter color) across subjects, according to MG (blue) and MP (red) data. Green dots represent taxa found conserved (dark) or variable (light) based on both MG and MP data. Dot size is proportional to the mean relative abundance of the corresponding taxon. 1 Azospirillum, 2 Acetobacter, 3 Escherichia, 4 Enterobacter, 5 Parasutterella, 6 Sutterella, 7 Bacteroides, 8 Alistipes, 9 Mucinivorans, 10 Prevotella, 11 Alloprevotella, 12 Paraprevotella, 13 Porphyromonas, 14 Barnesiella, 15 Odoribacter, 16 Tannerella, 17 Butyricimonas, 18 Holdemanella, 19 Bacillus, 20 Streptococcus, 21 Acidaminococcus, 22 Phascolarctobacterium, 23 Megasphaera, 24 Dialister, 25 Peptoclostridium, 26 Intestinimonas, 27 Flavonifractor, 28 Anaerotruncus, 29 Ruminococcus, 30 Subdoligranulum, 31 Faecalibacterium, 32 Lachnoclostridium, 33 Dorea, 34 Butyrivibrio, 35 Coprococcus, 36 Marvinbryantia, 37 Akkermansia, 38 Brachyspira, 39 Bifidobacterium, 40 Gordonibacter, 41 Desulfovibrio. b Bar graphs showing the 10 KEGG orthology functional groups with higher CV (variable, darker color) and the 10 with lower CV (conserved, lighter color) across subjects, according to MG (left, blue) and MP (right, red) data. Subunit names are shown into brackets. Only functional groups detected in at least half of the subjects are shown. MO monooxygenase, IF initiation factor, PRN polyribonucleotide, GMP guanosine monophosphate, LL-DAP l,l-diaminopimelate, 5P 5-phosphate