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Table 4 The outcomes of the logistic and negative binomial components of the fitted ZINB regression model

From: Oxalobacter formigenes-associated host features and microbial community structures examined using the American Gut Project

 

Logistic regression component

Negative binomial regression component

Estimate ± Std. error

z value

Pr(>|z|)a

Estimate ± Std. error

z value

Pr(>|z|)a

Intercept

10.133 ± 0.449

−22.545

<.001

−8.262 ± 0.240

−34.376

<.001

Age

−0.025 ± 0.007

−3.593

<.001

0.004 ± 0.003

1.108

0.268

Sex

    

 Female

Reference category

 Male

−0.422 ± 0.176

−2.403

0.016

−0.122 ± 0.090

−1.348

0.178

Race

    

 Caucasian

Reference category

 Asian/Pacific Islander

1.335 ± 0.371

3.602

<.001

−0.391 ± 0.310

−1.260

0.208

 Hispanic

−0.162 ± 0.529

−0.307

0.759

−0.273 ± 0.328

−0.834

0.404

 African American

0.542 ± 1.132

0.479

0.632

−0.223 ± 0.642

−0.347

0.728

 Other

0.408 ± 0.517

0.789

0.430

−0.058 ± 0.271

−0.214

0.831

BMI

    

 Underweight

0.081 ± 0.325

0.248

0.804

−0.278 ± 0.179

−1.551

0.121

 Normal

Reference category

 Overweight

0.071 ± 0.257

0.278

0.781

−0.384 ± 0.107

−3.571

<.001

 Obese

0.864 ± 0.317

2.723

0.006

−0.694 ± 0.168

−4.119

<.001

Freq. of alcohol consumption

    

 Never

Reference category

 Rarely

−0.802 ± 0.288

−2.786

0.005

−0.041 ± 0.134

−0.306

0.759

 Occasionally

−0.661 ± 0.269

−2.456

0.014

−0.104 ± 0.138

−0.754

0.451

 Regularly

−0.524 ± 0.287

−1.825

0.068

−0.212 ± 0.144

−1.470

0.142

 Daily

−0.608 ± 0.343

−1.774

0.076

−0.208 ± 0.169

−1.233

0.218

Last exposure to antibiotics (days)

    

 >365

Reference category

 <365

0.648 ± 0.246

2.632

0.008

−0.136 ± 0.125

−1.084

0.278

 <180

1.687 ± 0.273

6.188

<.001

0.115 ± 0.161

0.710

0.477

 <30

0.568 ± 0.469

1.212

0.226

−0.105 ± 0.263

−0.401

0.689

 <7

1.633 ± 0.519

3.149

0.002

0.334 ± 0.374

0.892

0.372

Country of residence

    

 USA

Reference category

 UK–Ireland

−2.802 ± 1.037

−2.703

0.007

0.180 ± 0.113

1.590

0.112

 Europe Continental

−1.598 ± 1.380

−1.158

0.247

0.258 ± 0.289

0.892

0.372

 Australia and NZL

−1.494 ± 0.982

−1.522

0.128

0.148 ± 0.227

0.654

0.513

 Canada

−1.470 ± 0.931

−1.578

0.115

−0.150 ± 0.304

−0.494

0.621

 Others

−2.299 ± 1.083

−2.123

0.034

0.384 ± 0.580

0.661

0.509

Drinking water source

    

 City

Reference category

 Filtered

0.094 ± 0.190

0.493

0.622

−0.053 ± 0.094

−0.558

0.577

 Bottled

−0.207 ± 0.393

−0.527

0.598

−0.020 ± 0.164

−0.121

0.904

 Well

0.407 ± 0.295

1.381

0.167

0.137 ± 0.167

0.822

0.411

Level of education

    

 ≤High school

0.957 ± 0.441

2.170

0.030

0.226 ± 0.239

0.945

0.344

 College/bachelor’s

Reference category

 Graduate school

0.176 ± 0.292

0.601

0.548

0.067 ± 0.111

0.602

0.547

Dog

    

 Absent

Reference category

 True

0.270 ± 0.178

1.516

0.130

−0.044 ± 0.094

−0.469

0.639

C-section

    

 False

Reference category

 True

0.209 ± 0.266

0.786

0.432

0.173 ± 0.151

1.143

0.253

Vegetable frequency

    

 <1 time/week

0.102 ± 0.630

0.162

0.871

−0.191 ± 0.330

−0.580

0.562

 1–2 times/week

0.395 ± 0.399

0.991

0.322

−0.099 ± 0.205

−0.485

0.628

 3–5 times/week

Reference category

 Daily

−0.216 ± 0.288

−0.750

0.453

0.184 ± 0.114

1.618

0.106

Thyroid condition

    

 No condition

Reference category

 Diagnosed

−0.093 ± 0.431

−0.216

0.829

−0.394 ± 0.166

−2.37

0.018

  1. aStatistical significance in italics