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Fig. 1 | Microbiome

Fig. 1

From: Influenza A virus infection impacts systemic microbiota dynamics and causes quantitative enteric dysbiosis

Fig. 1

Influenza A virus causes transient pathology in mice. a IAV causes transient body weight loss. Average relative initial body weight (%) ± SD is depicted for mock-treated (black line, n ≥ 18 per sample time point) and IAV-infected (red line, n ≥ 18 per sample time point). Pooled data from two independent experiments are shown. b Left side: representative thermal pictures of mock-treated and IAV-infected animals (lower panels), 7 dpi. Right side: quantification of core body temperature on days 3, 5, and 7 post infection, for mock-treated (black squares) and IAV-infected (red triangles) mice, median core temperature is indicated. Pooled data from two independent experiments are shown (n = 20 per time point, per group). c Individual total organ titers of mock-treated (black squares) and IAV-infected mice (red triangles), median titers (pfu/organ) are indicated. Limit of detection (LoD) 50 pfu is indicated by dotted line (n = 5 per time point, per group). d H&E stainining of mock-treated (left) and IAV-infected (right) mouse lungs (n = 6 per group from two independent experiments). Two representative lungs with indications for magnifications are shown. Lower panels: magnification of healthy vs. inflamed tissue

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