Fig. 3

Metaproteomics reveals protein abundance profiling between symptomatic and non-symptomatic samples. a Bacterial and host defence-associated proteins detected in AOD symptomatic tissue. Heatmap of MAD-scaled log₁₀ counts for proteins detected in symptomatic samples but not detected in non-symptomatic samples. The colour key depicts the log₁₀ MAD scale of protein counts in the different symptomatic samples. b Pathogenic and host defence-associated proteins differently abundant in symptomatic samples, depicting the increase of bacterial virulence-associated proteins in symptomatic tissue compared to non-symptomatic. Proteins were determined as significant using a t test on MAD normalised proteins of interest. Circles in light grey going out from the centre indicate the different log₂ fold changes, with the numbers indicated to the side of the plots