Fig. 4

Reduced antimicrobial peptide production from NOD Paneth cells is partly restored by introduction of a protective MHC haplotype. a Representative images of H&E stained sections of ileum crypt termini. b Lysozyme P staining of crypt termini (brown). c Quantification of lysozyme P staining intensity per crypt. Gene expression of Lysozyme P (d) and cryptdin (e) relative to HPRT in terminal ileum tissue