Skip to main content
Fig. 3 | Microbiome

Fig. 3

From: High salt diet exacerbates colitis in mice by decreasing Lactobacillus levels and butyrate production

Fig. 3

High salt diet exacerbates DSS colitis. a DSS colitis macroscopic scores at endpoint (day 7) in four groups of mice: control (control diet, no DSS), HSD (high salt diet, no DSS), control+DSS (control diet, DSS in water), HSD + DSS (high salt diet, DSS in water). b Body weight changes during DSS administration. c Colon length at endpoint. d Colonic MPO of the two groups of mice receiving DSS. e Survival curve of the two groups of mice with DSS colitis. f Heatmap of differentially expressed genes (p < 0.05) in the colon of mice with DSS colitis: C + D (control diet+DSS), HS + D (HSD + DSS). The heatmap was generated based on group average using Euclidean distance metric. Colitis scores, weight change, colon length, and MPO are presented as means ± SEM; n = 8–9 mice/group. *p < 0.05, **p < 0.01, #p < 0.001, ##p < 0.0001

Back to article page