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Fig. 7 | Microbiome

Fig. 7

From: Predominant gut Lactobacillus murinus strain mediates anti-inflammaging effects in calorie-restricted mice

Fig. 7

L. murinus CR147 increases the brood sizes and lifespan of C. elegans without changing egg-laying schedules. Worms were synchronized at L4-stage larvae at day 0. The egg-laying schedules and brood sizes of the worms fed a 1:9 mixture of E. coli OP50 and a L. murinus CR141 (OP50, n = 15; OP50:CR141 = 1:9, n = 14) or b L. murinus CR147 (OP50, n = 14; OP50:CR147 = 1:9, n = 15). Data are shown as the mean ± s.e.m. c Survival curves of C. elegans fed a 1:9 mixture of OP50 and L. murinus compared with the lifespan of the worms fed OP50 alone (OP50, n = 111; OP50:CR141 = 1:9, n = 116; OP50:CR147 = 1:9, n = 119). Each mNGM plate contained 10 mg of bacteria (wet weight). Differences were assessed by unpaired t test (two-tailed) (a, b) or log-rank test (c). ns, no significant difference; **P < 0.01 vs OP50 group (control). n indicates the number of worms per group

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