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Fig. 2 | Microbiome

Fig. 2

From: Similarity of the dog and human gut microbiomes in gene content and response to diet

Fig. 2

Effects of diet on the dog gut microbiome. a Study design (CHO carbohydrates, LPHC lower protein higher carbohydrates, HPLC high-protein low-carbohydrates). b Phylum-level relative abundances in the three diets; data is paired so that adjacent bars represent data from the same dog (before and after dietary intervention). c Principal coordinate analysis (using Bray-Curtis on log-transformed data as the underlying distance measure) based on taxonomic composition at the genus level (top panel) and the distributions of samples along the first principal component by diet and phenotype (bottom panel), *p < 0.05, **p < 0.01, ***p < 0.001; testing using Mann-Whitney-Wilcoxon test, after multiple hypothesis using the two-step Benjamini-Hochberg method; n.s. non-significant. d Shifts in microbiome composition vary for different diets and phenotype. The differences in relative abundance between the baseline and the post-treatment sample from the same dog, measured as Bray-Curtis (BC) distance after log-transformation (*p < 0.05, **p < 0.01, ***p < 0.001)

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