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Table 1 Socio-demographic and microbiological characteristics of subjects

From: Increased richness and diversity of the vaginal microbiota and spontaneous preterm birth

Characteristics

Term pregnancies (n = 170)

Preterm pregnancies (n = 46)

p value

Age (mean ± SD, range)1

33.6 ± 4.2 (21–45)

33.65 ± 4.1 (25–45)

0.948

 21–25

5 (2.9%)

1 (2.1%)

 

 26–35

114 (67.1%)

32 (69.5%)

 36–45

51 (30.0%)

13 (28.2%)

BMI (mean ± SD, range)1

22.9 ± 3.8 (17–40)

24.2 ± 5.6 (19–43)

0.125

 Underweight (< 18.50)

7 (4.1%)

0 (0%)

 

 Normal weight (18.51–24.9)

131 (77.0%)

33 (73.3%)

 Overweight (25.0–29.9)

25 (14.7%)

8 (17.7%)

 Obese (> 30)

7 (4.1%)

4 (9.0%)

 MD3

0 (0%)

1 (2.2%)

Ethnicity2

0.261

 White

108 (63.5%)

22 (47.8%)

 

 East Asian

26 (15.3%)

6 (13.0%)

 South/Southeast Asian

15 (8.8%)

4 (8.7%)

 Latin America/Hispanic

8 (4.7%)

3 (6.5%)

 Black

3 (1.8%)

2 (4.4%)

 Other/mixed ethnicity

10 (5.9%)

6 (13.0%)

 MD

0 (0%)

3 (6.5%)

Community state type (CST)2

0.361

 I

56 (32.9%)

17 (37%)

 

 II

9 (5.3%)

5 (10.9%)

 III

28 (16.5%)

8 (17.4%)

 IVA

31 (18.2%)

6 (13%)

 IVC

19 (11.2%)

2 (4.3%)

 IVD

11 (6.5%)

1 (2.2%)

 V

16 (9.4%)

7 (15.2%)

Estimated bacterial load (log copies of 16S rRNA gene)/swab (mean ± SD, range)1

7.78 ± 0.93 (4.89–10.67)

8.07 ± 0.71 (6.32–10.33)

0.049

Presence of Mollicutes2

68 (40%)

28 (60.8%)

0.012

Presence of Ureaplasma2

40 (23.4%)

14 (30.4%)

0.337

 U. parvum

37 (21.7%)

14 (30.4%)

 

 U. urealyticum

3 (1.7%)

0 (0%)

Shannon diversity (mean ± SD, range)1

1.28 ± 0.86 (0.13–4.52)

1.81 ± 1.13 (0.34–5.16)

0.004

Chao1 richness (mean ± SD, range)1

36.22 ± 14.80 (14.39–115.74)

46.38 ± 24.19 (20.20–126.01)

0.009

  1. 1t test; 2chi-square; 3MD = missing data