Pathway | HMM-GRASPx | MetaCLADE/HMM-GRASPx-Assemblyc | MetaCLADE/GC-Assemblyd | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TP | FP | FN | Recall | Prec | F-score | TP | FP | FN | Recall | Prec | F-score | TP | FP | FN | Recall | Prec | F-score | |
“Strict” domain annotationa | ||||||||||||||||||
KO00010 | 159 243 | 2 216 | 39 938 | 79. 9 | 98.6 | 88.3 | 171 168 | 5 384 | 24 845 | 87.3 | 97.0 | 91.9 | 179 972 | 7 397 | 14 028 | 92.8 | 96.1 | 94.4 |
KO00020 | 182 706 | 11 691 | 74 704 | 71.0 | 94.0 | 80.9 | 201 808 | 24 786 | 42 507 | 82.6 | 89.1 | 85.7 | 223 671 | 20 452 | 24 978 | 90.0 | 91.6 | 90.8 |
KO00030 | 101 449 | 589 | 17 761 | 85.1 | 99.4 | 91.7 | 107 065 | 833 | 11 901 | 90.0 | 99.2 | 94.4 | 113 446 | 859 | 5 494 | 95.4 | 99.2 | 97.3 |
KO00051 | 436 432 | 17 970 | 192 918 | 69.3 | 96.0 | 80.5 | 482 994 | 50 714 | 113 612 | 81.0 | 90.5 | 85.5 | 553 728 | 41 566 | 52 026 | 91.4 | 93.0 | 92.2 |
KO00620 | 237 743 | 11 756 | 100 903 | 70.2 | 95.3 | 80.8 | 263 011 | 27 306 | 60 085 | 81.4 | 90.6 | 85.8 | 297 162 | 21 038 | 32 202 | 90.2 | 93.4 | 91.8 |
KO00680 | 595 304 | 24 101 | 229 802 | 72.1 | 96.1 | 82.4 | 633 158 | 74 709 | 141 340 | 81.8 | 89.4 | 85.4 | 695 625 | 70 569 | 83 013 | 89.3 | 90.8 | 90.1 |
KO00910 | 219 501 | 16 171 | 86 939 | 71.6 | 93.1 | 81.0 | 238 683 | 30 435 | 53 493 | 81.7 | 88.7 | 85.0 | 264 438 | 25 270 | 32 903 | 88.9 | 91.3 | 90.1 |
KO00920 | 74 851 | 138 | 37 662 | 66.5 | 99.8 | 79.8 | 82 977 | 1 098 | 28 576 | 74.4 | 98.7 | 84.8 | 105 794 | 603 | 6 254 | 94.4 | 99.4 | 96.9 |
“Clan-based” domain annotationb | ||||||||||||||||||
KO00010 | 161 459 | 0 | 39 938 | 80.2 | 100.0 | 89.0 | 176 369 | 183 | 24 845 | 87.7 | 99.9 | 93.4 | 187 308 | 61 | 14 028 | 93.0 | 100.0 | 96.4 |
KO00020 | 194 397 | 0 | 74 704 | 72.2 | 100.0 | 83.9 | 226 585 | 9 | 42 507 | 84.2 | 100.0 | 91.4 | 244 114 | 9 | 24 978 | 90.7 | 100.0 | 95.1 |
KO00030 | 102 038 | 0 | 17 761 | 85.2 | 100.0 | 92.0 | 107 867 | 31 | 11 901 | 90.1 | 100.0 | 94.8 | 114 275 | 30 | 5 494 | 95.4 | 100.0 | 97.6 |
KO00051 | 454 402 | 0 | 192 918 | 70.2 | 100.0 | 82.5 | 533 583 | 125 | 113 612 | 82.4 | 100.0 | 90.4 | 594 999 | 295 | 52 026 | 92.0 | 100.0 | 95.8 |
KO00620 | 249 492 | 7 | 100 903 | 71.2 | 100.0 | 83.2 | 288 167 | 2 150 | 60 085 | 82.7 | 99.3 | 90.3 | 317 646 | 554 | 32 202 | 90.8 | 99.8 | 95.1 |
KO00680 | 618 689 | 716 | 229 802 | 72.9 | 99.9 | 84.3 | 701 356 | 6 511 | 141 340 | 83.2 | 99.1 | 90.5 | 756 885 | 9 309 | 83 013 | 90.1 | 98.8 | 94.3 |
KO00910 | 235 260 | 412 | 86 939 | 73.0 | 99.8 | 84.3 | 267 624 | 1 494 | 53 493 | 83.3 | 99.4 | 90.7 | 288 068 | 1 640 | 32 903 | 89.7 | 99.4 | 94.3 |
KO00920 | 74 989 | 0 | 37 662 | 66.6 | 100.0 | 79.9 | 84 053 | 22 | 28 576 | 74.6 | 100.0 | 85.5 | 106 392 | 5 | 6 254 | 94.4 | 100.0 | 97.1 |