Fig. 3
From: Enterobacteriaceae are essential for the modulation of colitis severity by fungi
Vancomycin and colistin have different effects on DSS-induced colitis. a Experimental design for the administration of vancomycin or colistin antibiotics, and dextran sulfate sodium (DSS). b Weight of DSS-exposed mice. For statistical comparisons, an asterisk (*) indicates vancomycin versus colistin/H2O. c Disease activity index (DAI) of DSS-exposed mice. For statistical comparisons, an asterisk (*) indicates vancomycin versus H2O. d IFN-γ (left) and Reg3g (right) transcript expression in the colon after initiation of DSS treatment. e Secreted lipocalin (pg/mg of feces) in the feces of mice treated with vancomycin (V), colistin (C), and vehicle (H2O). Throughout, data are presented as the mean ± s.e.m. *P < 0.05, **P < 0.01, and ***P < 0.001 by one-way ANOVA with a post hoc Tukey or Dunn’s test; n = 12 mice per group from two independent experiments