Fig. 4

Schematic representation of the four main levels governing pathofunction activity and potential host damage (red)—details on the three examples, i.e., the formation of trimethylamine (TMA, via CutCD, CntAB, and GrdH), the secondary bile acids lithocholic/deoxycholic acid (LCA/DCA, via enzymes encoded in the bai operon), and hydrogen sulfide (H₂S, via DsrAB) are given. Possibilities for intervention are shown in blue. For more information see text