Fig. 4

Feature importance from random forest classifiers for CD versus HCs in addition to feature abundance. Results from OTU and genus classifiers are shown in figures a and b, respectively. The corresponding genera of OTU features were labeled for the ease of interpretation. Each heatmap displays the abundance of the top ten features (rows) in samples (columns) according to the machine learning classifiers. The column bar colors represent the categories of the samples. Feature importance is shown on the right, and features are ordered in decreasing importance from top to bottom according to the mean decrease in Gini index