Compositionally and functionally distinct sinus microbiota in chronic rhinosinusitis patients have immunological and clinically divergent consequences

Cope, Emily K.; Goldberg, Andrew N.; Pletcher, Steven D.; Lynch, Susan V.

doi:10.1186/s40168-017-0266-6

Table 1 Demographics of CRS patients and healthy subjects included in this study

From: Compositionally and functionally distinct sinus microbiota in chronic rhinosinusitis patients have immunological and clinically divergent consequences

Sample ID	Age	Gender	Disease	Pre-operative antibiotics <3 months	Lund-Mackay score	Polyp	Status
33	47	F	CRS+CF	Multiple (>3)	22	N	Included
36	27	F	CRS+CF	Multiple (>3)	18	Y	Included
39	28	M	CRS+CF	Multiple (>3)	13	N	Included
61	20	M	CRS+CF	Azithromycin	15	Y	Included
64	71	M	CRS+CF	Dicloxacillin	16	Y	Included
83	24	M	CRS+CF	Multiple	19	Y	Included
90	20	F	CRS+CF	Ceftrioxone	19	Y	Included
91	47	M	CRS+CF	Zithromax/dapsone	17	Y	Included
108	30	M	CRS+CF	Multiple (>3)	16	Y	Included
1	41	M	CRS	Augmentin	5	N	Included
7	39	F	CRS	Augmentin	12	N	Included
8	55	F	CRS+Asthma	Augmentin	23	Y	Included
15	55	M	CRS+Asthma	Clarithromycin	15	N	Included
16	51	M	CRS	Augmentin	22	N	Included
17	61	F	CRS+Asthma	Multiple (>3)	12	N	Included
22	58	M	CRS+Asthma	Bactrim	12	Y	Included
32	19	M	CRS	Augmentin	22	Y	Included
34	51	M	CRS+Asthma	Levofloxacin	5	N	Included
40	72	F	CRS	Tobramycin	9	N	Included
43	46	M	CRS	Augmentin	12	N	Included
44	62	M	CRS	Levofloxacin	20	Y	Included
54	71	M	CRS+Asthma	dicloxacillin	13	Y	<10,000 sequences/sample
55	68	F	CRS+Asthma	Clotrimazole	21	Y	Included
56	67	F	CRS	Augmentin/Bactrim	14	Y	Included
58	85	M	CRS	Ampicillin/sulbactam	ND^a	ND	No PCR product
59	42	F	CRS+Asthma	Clindamycin	4	Y	Included
60	35	M	CRS	Multiple (>3)	16	N	Included
63	77	F	CRS	Levofloxacin	6	N	Included
80	58	M	CRS	Augmentin	8	N	Included
81	65	F	CRS+Asthma	Augmentin	10	N	Included
82	28	M	CRS	Augmentin	9	Y	Included
85	24	F	CRS+Asthma	Augmentin	4	N	Included
86	88	F	CRS	None	19	Y	Included
88	73	M	CRS	None	21	Y	Included
89	52	M	CRS	Clarithromycin	ND	ND	No PCR product
92	59	M	CRS	Multiple (>3)	13	N	Included
93	48	M	CRS	Azithromycin/augmentin	11	Y	Included
94	72	F	CRS+Asthma	Augmentin	8	N	Included
96	54	M	CRS	Cephalexin	11	Y	Included
97	52	M	CRS	Cetirizine	22	Y	Included
98	39	M	CRS+Asthma	Multiple (>3)	16	Y	Included
99	57	M	CRS	Levofloxacin	16	Y	Included
100	62	F	CRS	Bactrim	4	N	Included
101	27	M	CRS+Asthma	Azithromycin	ND	Y	Included
103	36	M	CRS	Augmentin	10	Y	Included
104	23	M	CRS	None	12	N	Included
105	18	M	CRS	None	21	N	Included
107	37	F	CRS	Cephalexin	7	Y	Included
109	71	M	CRS+Asthma	Augmentin	11	Y	Included
110	18	F	CRS	Multiple (>3)	16	N	Included
111	59	M	CRS	Augmentin	10	N	Included
112	48	F	CRS	Augmentin	9	N	Included
114	37	F	CRS	Clindamycin	1	N	Included
115	26	F	CRS	Augmentin	3	N	Included
117	33	M	CRS	Ciprofloxacin	19	N	Included
120	50	F	CRS+Asthma	Multiple (>3)	15	Y	Included
121	33	F	CRS	Augmentin	9	Y	Included
122	45	F	CRS+Asthma	Augmentin	21	Y	Included
123	74	M	CRS+Asthma	Augmentin	16	Y	Included
124	30	M	CRS+Asthma	Augmentin	6	N	<10,000 sequences/sample
126	43	F	CRS+Asthma	Augmentin	11	Y	<10,000 sequences/sample
128	69	M	CRS+Asthma	Bactrim	21	Y	Included
130	59	M	CRS+Asthma	Augmentin	17	Y	Included
132	48	M	CRS	Rifampin	13	N	<10,000 sequences/sample
143	61	M	CRS	Augmentin	ND	N	Included
30	38	M	Healthy	Topical bacitracin	ND	N	<10,000 sequences/sample
31	59	M	Healthy	Amoxicillin/azithromycin	ND	N	Included
131	59	F	Healthy^b	None	1	N	Included
CRS14	41	M	Healthy^b	None	ND	N	Included
CRS15	39	M	Healthy	None	ND	N	Included
CRS16	37	F	Healthy	None	ND	N	Included
CRS17	46	F	Healthy	None	ND	N	Included
CRS18	46	M	Healthy	None	ND	N	Included
CRS19	31	F	Healthy	None	ND	N	Included
CRS20	18	F	Healthy	None	ND	N	Included
ctrl4	22	M	Healthy	None	ND	N	Included

^a ND not determined
^b Allergic rhinitis

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ISSN: 2049-2618

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