Table 1 Distribution of abundant families in mouse fecal samples treated with a single course of antibiotics. Family abundances were averaged over all post-gavage time points and are presented as mean ± standard error. ANOVA were performed for each family and, where significant differences were observed, letters denote significant differences by Tukey’s post hoc test (P < 0.05)
Antibiotics | Systemic | Non-absorbable | ANOVA | ||
|---|---|---|---|---|---|
Purgative | Yes | No | Yes | No | P value |
Porphyromonadaceae | 30.72 ± 4.24 | 36 ± 2.76 | 37.2 ± 3.42 | 39.19 ± 1.68 | 0.267 |
Lactobacillaceae | 0.03 ± 0.02 A | 0.02 ± 0.01 A | 6.44 ± 0.86 B | 7.62 ± 1.15 B | <0.001 |
Lachnospiraceae | 23.29 ± 4.69 AB | 27.23 ± 3.45 A | 13.46 ± 2.16 B | 19.32 ± 2.95 AB | 0.027 |
Bacteroidaceae | 24.01 ± 3.45 A | 16.43 ± 2.02 AB | 19.36 ± 3.15 AB | 14.02 ± 1.31 B | 0.044 |
Clostridiaceae_1 | 2.80 ± 1.05 A | 0.84 ± 0.26 B | 0.06 ± 0.04 B | 0.05 ± 0.02 B | 0.001 |
Ruminococcaceae | 2.57 ± 0.49 | 4.31 ± 0.56 | 3.86 ± 0.43 | 3.91 ± 0.36 | 0.065 |
Erysipelotrichaceae | 2.31 ± 0.46 | 3.05 ± 0.86 | 2.36 ± 0.41 | 3.74 ± 0.94 | 0.464 |
Enterobacteriaceae | 5.01 ± 1.30 A | 3.08 ± 1.14 AB | 4.15 ± 1.31 AB | 0.68 ± 0.29 B | 0.039 |
Acidaminococcaceae | 3.01 ± 0.48 | 2.25 ± 0.35 | 3.71 ± 0.67 | 3.25 ± 0.54 | 0.197 |