Table 2 Overview of individual datasets included in this study

I

Jie et al. [21]

CVD (n = 218) vs. controls (n = 186)

A

II

Karlsson et al. [22]

CVD (n = 13) vs. controls (n = 12)

E

III

Qin et al. [23]

T2D (n = 182) vs. controls (n = 185)

A

IV

Forslund et al. [24]

T2D (n = 75), T1D (n = 31) vs. samples from VI

E

V

Karlsson et al. [25]

T2D (n = 43) vs. controls (n = 53)

E

VI

Le Chatelier et al. [26]

Obese (n = 161) vs. controls (n = 109)

E

VII

Feng et al. [27]

CRC (n = 46), LA (n = 47) vs. controls (n = 63)

A/E

VIII

Zeller et al. [28]

CRC (n = 91), LA (n = 15), SA (n = 27) vs. controls (n = 66)

E

IX

Vogtmann et al. [29]

CRC (n = 52) vs. controls (n = 52)

NA

X

Qin et al. [30]

Cirrhosis (n = 123) vs. controls (n = 114)

A

XI

Qin et al. [31]

UC (n = 21), CD (n = 4) vs. controls (n = 14)

E

XII

Schirmer et al. [32]

MTG: UC (n = 78), CD (n = 175) vs. controls (n = 55)

NA

MTX: UC (n = 46), CD (n = 121) vs. controls (n = 11)

XIII

Mehta et al. [53]

MTG and MTX of 78 subjects (4 time points)

NA