Fig. 3From: Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancerBacteria interactions with target CRC TSGs. a Significant positive bacteria interactions involving MLH1, APC, PTEN, P16, CDX1, and CDX2. Line width = −log (P). b Left: Violin plot of MLH1 methylation versus Streptococcus spp. Right: APC versus H. hathewayi. Methylation levels of both genes increased as the bacteria abundance elevatedBack to article page