Fig. 6
From: β-glucan attenuates cognitive impairment via the gut-brain axis in diet-induced obese mice
Short-term β-glucan supplementation prevented HFFD-induced gut microbiota alteration prior to cognitive improvement. Cecal content microbiota composition was analyzed by 16S rRNA gene sequencing (n = 5–6) (a–d). a Principal coordinates analysis plot of weighted UniFrac distances. b Composition of abundant bacterial phyla. c Comparison of the representative taxonomic abundance at phylum. d Linear discriminant analysis (LDA) effect size showing the most differentially significant abundant taxa enriched in microbiota from the HFBG and HFFD. Values are mean ± SEM. *p < 0.05 vs. control (Con). #p < 0.05 vs. high-fat and fiber-deficient diet (HFFD). Abbreviations: p, phylum