Fig. 4

Prevotella is associated with non-responders to chemoradiotherapy at baseline. A β-diversity shown by NMDS plot, (B) diversity, and (C) richness of the salivary microbiome sampled before treatment in SCC patients that were responders (R) (i.e., no local or distant recurrences) versus non-responders (NR) to chemoradiotherapy. D Relative abundance of salivary bacteria at the phylum level between responders and non-responders at baseline. E Relative abundance of the bacterial families Porphyromonadaceae, Prevotellaceae, Streptococcocaceae, and Fusobacteriaceae. F LEfSe analysis showing the most differentially abundant OTUs at baseline between responders versus non-responders and (G) their relative abundances