Fig. 7

Salivary DMBT1 is reduced in mice after tumor development. A Schematic showing the timing of saliva collection. UM-SCC-1 cells or matrigel (control) were injected subcutaneously into athymic nude mice and whole stimulated saliva was collected. B Tumor volume was measured for 60 days. C Representative tumor section stained with hematoxylin–eosin and cytokeratin antibody. Scale bar = 500 µm in the left panel and 200 µm in the right panel. D Densitometric quantification of immunoblot data normalized to saliva volume collected at two time points (S1 and S2) in each adult mouse and differences tested by paired t test. E Each DMBT1 measure from immunoblot quantification was log-transformed