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Table 2 Demographics distribution by chemoradiotherapy response (Figs. 4 and 5)

From: Salivary microbiome changes distinguish response to chemoradiotherapy in patients with oral cancer

Variable

 

Responders (n = 39)

Non-responders (n = 11)

 

n or mean (std)

n or mean (std)

p value

Age

Years

58.5 (7.6)

61.7 (9.9)

0.26

Gender

Male

32

8

0.49

Female

7

3

 

Clinical stage

0/1

-

-

0.34

2

1

1

 

3

3

2

 

4

35

8

 

T stage

T1

5

1

0.95

T2

11

4

 

T3

9

2

 

T4

13

4

 

X

1

-

 

N stage

N0

3

3

0.31

N1

3

1

 

N2

31

7

 

N3

2

-

 

Disease site

Larynx

7

3

0.21

Oral cavity

-

1

 

Oropharynx

31

7

 

Unknown primary

1

-

 

ACE comorbidities Score

None

12

3

0.79

Mild

20

5

 

Moderate

6

2

 

Severe

1

1

 

BMI

Normal (15.5–24.9)

7

4

0.34

Overweight (25–29.9)

18

5

 

Obese (30 +)

14

2

 

HPV status

Negative

7

6

0.04

Positive

29

4

 

Unknown

3

1

 

Drinker

Never

-

1

0.16

Current

28

7

 

Former (quit > 12 months)

11

3

 

Smoker (cigarettes)

Never

11

-

0.14

Current

16

6

 

Former (quit > 12 months)

12

5

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