Table 4 Demographics distribution of patients used in microbiome and DMBT1 change correlation (Fig. 8)

Age

Years

57.1 (7.2)

59.2 (9.9)

0.62

Gender

Male

12

2

0.27

Female

3

3

Clinical stage

2

1

-

1.00

3

2

1

4

12

4

T stage

T1

2

1

0.67

T2

8

1

T3

2

2

T4

3

1

N stage

N0

1

2

0.17

N1

3

0

N2

11

3

Disease site

Larynx

1

1

0.25

Oral cavity

2

-

Oropharynx

12

3

Nasopharynx

0

1

Treatment

Chemotherapy

0

1

0.15

Surgery

3

-

Chemoradiotherapy

12

4

ACE comorbidities score

None

5

1

0.36

Mild

8

3

Moderate

2

-

Severe

0

1

BMI

Normal (15.5–24.9)

2

-

0.84

Overweight (25–29.9)

6

3

Obese (30 +)

7

2

HPV status

Negative

3

3

0.25

Positive

12

2

Drinker

Never

1

-

1.00

Current

13

4

Former (quit > 12 months)

1

1

Smoker (cigarettes)

Never

5

-

0.04

Current

7

1

Former (quit > 12 months)

3

4