Fig. 1

Screening of IFN-I-inducing bacterial strain from human feces. a Scatter plot displaying a colorimetric assay using an IFN α/β reporter cell line. b Heat map and mRNA levels for ISGs (Oas1, Cxcl10, Ifit1, Ifit3, Rsad2, Oasl2, Irf7, and Mx1) and pro-inflammatory cytokines (IL-1β, IL-6, and IL-18) from lung tissues. c Frequencies and absolute cell numbers of CD45⁺CD11c⁺PDCA-1⁺ and CD45⁺CD11b⁺Ly6G⁻Ly6C^hi cells in lung tissues. Statistical analyses were performed using one-way ANOVA with post hoc Tukey’s test. ^*p < 0.05, ^**p < 0.01, and ^***p < 0.001. Data were combined from at least three independent experiments