Skip to main content
Fig. 3 | Microbiome

Fig. 3

From: Newly isolated Lactobacillus paracasei strain modulates lung immunity and improves the capacity to cope with influenza virus infection

Fig. 3

Administration of L. paracasei MI29 enhances IFN-I-dependent resistance to virus infection. a Body weight changes of mice after A/PR8 infection. b Plaque assay using MDCK cell line for viral titer of lung and expression level of IFN-I in lung homogenate using ELISA at 2 dpi. c Pathology and scores of lung tissues from H&E staining. d Heat map and mRNA levels for ISGs (Oas1, Cxcl10, Ifit1, Ifit3, Rsad2, Oasl2, Irf7, and Mx1) and pro-inflammatory cytokines (IL-1β, IL-6, and IL-18) from lungs at 2 dpi. Statistical analyses were performed using a two-tailed paired t test. *p < 0.05, **p < 0.01, and ***p < 0.001. Data are combined from at least three independent experiments

Back to article page

Microbiome

ISSN: 2049-2618

Contact us