Fig. 6

DVF does not aggravate colitis in LRRC19 knockout mice. A Mouse genotypes were determined by PCR using the indicated primers to detect wild-type and mutant alleles of Lrrc19. B The experimental design of DSS model in WT and Lrrc19^−/− mice. C Body weight was presented as a percentage of the initial weight. D,E DAI (D) and colon length (E) are shown. F Representative histological images of colon tissues by H&E staining (left; Scale bars, 500 µm) and histopathological score (right). All data are presented as mean ± SEM. *P < 0.05, ** P < 0.01, *** P < 0.001, ns, not significant. One-way ANOVA in C–F