Fig. 3
Fecal metabolome is altered by phenylbutazone administration. A PCA with biplot of fecal metabolites grouped by treatment (NSAID or control) and day (day 0 = before treatment and day 10 = after treatment). Ellipses represent 95% CI around the group mean points. Point size indicates quality of representation (cos2) of individuals on the PCA; the larger point size reflects higher quality representation. The 4 genera highlighted by the red box are the genera selected by subsequent analyses. B Boxplots showing the percent relative abundance of the 4 genera selected by subsequent analyses. Horizontal line represents the median, box extends from 25 to 75th percentiles, and whiskers extend to minimum and maximum values